Paralogue Annotation for KCNQ1 residue 595

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 595
Reference Amino Acid: V - Valine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 595

No paralogue variants have been mapped to residue 595 for KCNQ1.



KCNQ1------------SEKSKDRGSNTIGARLNR>V<EDKVTQLDQRLALITDMLHQLLSLHGGS--623
KCNQ2------------PAEAELPEDPSMMGRLGK>V<EKQVLSMEKKLDFLVNIYMQRMGIPPTE--654
KCNQ3QQSPRNEPYVARPSTSEI-EDQSMMGKFVK>V<ERQVQDMGKKLDFLVDMHMQHMERLQVQ--653
KCNQ4------------PSDAEVVDEISMMGRVVK>V<EKQVQSIEHKLDLLLGFYSRCLRSGTSA--650
KCNQ5------------TAEHETTDDLSMLGRVVK>V<EKQVQSIESKLDCLLDIYQQVLRKGSASAL639
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1------------------------------>-<------------------------------
KCNB2------------------------------>-<------------------------------
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1------------------------------>-<------------------------------
KCND2------------------------------>-<------------------------------
KCND3------------------------------>-<------------------------------
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V595Lc.1783G>T Putative BenignSIFT:
Polyphen: