Paralogue Annotation for KCNQ1 residue 612

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 612
Reference Amino Acid: M - Methionine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 612

No paralogue variants have been mapped to residue 612 for KCNQ1.



KCNQ1DRGSNTIGARLNRVEDKVTQLDQRLALITD>M<LHQLLSLHGGS----------------TPG626
KCNQ2LPEDPSMMGRLGKVEKQVLSMEKKLDFLVN>I<YMQRMGIPPTE--TEAYFG--AKEPEPAPP669
KCNQ3I-EDQSMMGKFVKVERQVQDMGKKLDFLVD>M<HMQHMERLQVQ--VTE--------YYPTKG662
KCNQ4VVDEISMMGRVVKVEKQVQSIEHKLDLLLG>F<YSRCLRSGTSA--SLGAVQVPLFDPDITSD667
KCNQ5TTDDLSMLGRVVKVEKQVQSIESKLDCLLD>I<YQQVLRKGSASALALASFQIPPFECEQTSD656
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1------------------------------>-<------------------------------
KCNB2------------------------------>-<------------------------------
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1------------------------------>-<------------------------------
KCND2------------------------------>-<------------------------------
KCND3------------------------------>-<------------------------------
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Met612Ilec.1836G>A UnknownSIFT:
Polyphen: