Paralogue Annotation for KCNQ1 residue 649

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 649
Reference Amino Acid: D - Aspartate
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 649

No paralogue variants have been mapped to residue 649 for KCNQ1.



KCNQ1-----------------------------V>D<------------------------------649
KCNQ2TSWQPQSHPRQG----H-GTSPVGDHGSLV>R<IPPP-PAHERS-------------------751
KCNQ3FAHDPVNLPRGGPSSGKVQATPPSSATTYV>E<RPTVLPILTLL-------------------754
KCNQ4------------------------------>-<------------------------------
KCNQ5SAVAATNTIANQ----I-NTAPKPAAPTTL>Q<IPPPLPAIKHLPRPETLHPNPAGLQESISD779
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1------------------------------>-<--------------------IAF----NFE749
KCNB2------------------------------>-<--------------------FPF----SSR799
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1------------------------------>-<------------------------------
KCND2------------------------------>-<------------------------------
KCND3------------------------------>-<------------------------------
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.D649Nc.1945G>A Putative BenignSIFT:
Polyphen:
p.D649Gc.1946A>G Putative BenignSIFT:
Polyphen: