Paralogue Annotation for KCNQ1 residue 667

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 667
Reference Amino Acid: V - Valine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 667

No paralogue variants have been mapped to residue 667 for KCNQ1.



KCNQ1---------PELFLPS----NTLPTYEQLT>V<PRRGP-DEGS--------------------676
KCNQ2TSISIPSVDHEELERSFSGFSISQSKENLD>A<LNSCY-AAVAPCAK---------VRPYIAE836
KCNQ3TPLSLMSVNHEELERSPSGFSISQDRDDYV>F<GPNGG-SS---WMR---------EKRYLAE835
KCNQ4------------------------------>-<------------------------------
KCNQ5TLLSVCPMVPKDLGKSLSVQNLIRSTEELN>I<QLSGS-ESSGSRGSQDFYPKWRESKLFITD873
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1STSPKFSTG--TRSEKNHFESSPLPTSPKF>L<RQNCIYSTEAL-TGKGPSGQEKC-----KL833
KCNB2CFADKPSDGRDPLREEGSVGSSSPQDTGHN>C<RQDI-YHAVSE-VKKD-SSQEGC-----KM885
KCNC1------------------------------>-<-PTEA-VRV---------------------584
KCNC2------------------------------>-<-PVTS-PYNSP-------------------624
KCNC3------------------------------>-<-ANAA-AWIS--------------------756
KCNC4------------------------------>-<-PTAG-TLFLP-------------------634
KCND1---PDESQPSSPGGGGRAGSTLRNSSLGTP>C<LFPET-VKISS-------------------646
KCND2---PE--------GDDRPE--SP------E>Y<SGGNI-VRVSA-------------------629
KCND3---PE--------GESRPPPASPGPNTNIP>S<IASNV-VKVSA-------------------654
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V667Mc.1999G>A Putative BenignSIFT:
Polyphen: